Jeffrey Mann's Central/Peripheral Vertigo Table =============================================== CLINICAL FEATURES PERIPHERAL VERTIGO CENTRAL VERTIGO Intensity of vertigo moderate to intense mild to moderate Autonomic symptoms prominent and often worse less common (nausea, vomiting, when moving the head sweating) Nystagmus: (direction of the fast phase) Type horizontal or rotatory horizontal or rotatory jerk-type or vertical or asymmetric or bizarre Clinical features Decreases or ceases Unaffected or little when visually fixating. affected by fixation. Increases in intensity Increased intensity when the gaze is in the when covering the direction of the fast phase. fixating eye. Increased intensity when covering the fixating eye. Directionally fixed in all directions. May change direction gaze directions. in different gaze directions NB: 1. Nystagmus always increases when eyes are turned away from the fast phase (toward the slow phase): Alexander's Law. 2. Fixation is totally removed by applying Frenzel glasses that prevent fixation but allow visualization of nystagmus, may also look in one eye with ophthalmoscope and cover the other eye. Nystagmus only present Yes No in the dark Nystagmus present when No Yes fixating Features on Nylen- Has latentcy, fatigues and No latentcy or Barany testing adapts. fatiguing. Does not (Hallpike manuver) adapt. Otological symptoms may be present usually absent Risk factors for stroke may be absent usually present - hypertension, smoking, DM, vascular disease Neurological symptoms usually absent may be present - headache, face pain or paresthesias - blurred/double vision Neurological signs absent may be present - cranial nerve deficits - dysarthria, dysphagia - dysmmetria - Horner's syndrome - face/limb sensorimotor deficits - diplopia Gait possible, but tends to near-impossible & lean or fall towards one side very uncoordinated & falls to any side. preserved walking - but Falls when walking unidirectional postural and cannot even instability. ambulate. Definite indications for immediate neuro-imaging in acute vertigo include:- 1) Acute sudden headache. 2) Inability to ambulate. 3) Horizontal spontaneous nystagmus that changes directions with gaze. 4) Vertical spontaneous or positional nystagmus. 5) Any focal neuro signs. --Jeffrey Mann, adapted from "Acute vestibular sydrome," NEJM - September 3 1998