Sleep References ================ Bonnet MH, Arand DL The use of prophylactic naps and caffeine to maintain performance during a continuous operation Ergonomics 1994; 37:1009-20 After a normal baseline night of sleep and a morning of baseline test performance, 24 young adult male subjects returned to bed from 16:00-20:00 prior to a 24 h period of sleep loss. Twelve subjects received caffeine 200 mg at 01:30 and 07:30. Performance tests (correctly completed addition problems, vigilance sensitivity, and logical reasoning correct responses) all indicated maintenance of baseline performance levels in the caffeine group after administration of caffeine while performance declined in the placebo group. Similar results were found for the Multiple Sleep Latency Test and Oral Temperature, which both remained near baseline levels throughout the observation period in subjects receiving caffeine. The results indicated that the combination of a prophylactic nap and caffeine was more effective in maintaining nocturnal alertness and performance than was the nap alone. Of more interest was the fact that the group which was given the combination of nap and caffeine was able to maintain alertness and performance at very close to baseline levels throughout a 24 h period without sleep. Bonnet MH, Gomez S, Wirth O, Arand DL The use of caffeine versus prophylactic naps in sustained performance Sleep 1995; 18:97-104 Previous studies have shown that performance during sleep loss is improved by prophylactic naps as a function of varying nap length. Based on single-dose caffeine studies, a similar dose-response effect has been hypothesized on performance, alertness and mood during sleep loss. The present study compared the effects of repeated versus single-dose administration of caffeine and varying amounts of sleep taken prior to sleep loss on performance, mood and physiological measures during 2 nights and days of sleep loss. A total of 140 normal, young adult males participated at one of two study sites. Ninety-eight subjects at one site were randomly assigned to one of four nap conditions (0, 2, 4 or 8 hours) and 42 subjects at the second site were assigned to one of four caffeine conditions. After a normal baseline night of sleep and morning baseline tests of performance, mood and nap latency, subjects in the nap groups returned to bed at noon, 1600 hours, 1800 hours or not at all. Bedtimes were varied so that all naps ended at 2000 hours. Subjects in the caffeine groups received either a single 400-mg dose of caffeine at 0130 hours each night or repeated doses of 150 or 300 mg every 6 hours starting at 0130 hours on the 1st night of sleep loss. A placebo control group (no nap and placebo administered every 6 hours on the repeated caffeine schedule) was run at both sites.(ABSTRACT TRUNCATED AT 250 WORDS) Bonnet MH, Arand DL Impact of naps and caffeine on extended nocturnal performance Physiol Behav 1994; 56:103-9 It was hypothesized that alertness and performance during an extended work period would be improved by an afternoon nap and the subsequent use of caffeine during the night. Twelve young adults received a 4-h afternoon nap and caffeine during the night during one session and four 1-h naps during the night in a second session. After an afternoon nap, subjects had increased objective and subjective alertness, increased oral temperature, and increased performance on complex tasks like logical reasoning and correct additions when compared to the condition that allowed four nighttime naps. It was concluded that the specific scheduling of a nap period in preparation for an all-night work shift where sleep would not be allowed could result in increased alertness and performance as well as a less conflicted work situation.