Sarcoidosis
                        ===========
þ Staging
 - Stage I:  hilar adenopathy only
  + 75% resolve within 2 years
 - Stage II: hilar adenopathy and diffuse infiltrates
  + more sx than Stage I
  + 50% will resolve within 2 years
 - Stage III: diffuse infiltrates only
  + 33% will resolve in 2 years.
  + May go on to fibrosis.

þ Alveolar sarcoidosis
 - diffuse infiltrates

þ Necrotizing Sarcoid Granulomatosis
 - variant

þ Extrapulmonary:
 - uveitis:
  + 2-4% of uveitis is sarcoid
  + anterior uveitis: tearing, photophobia, little or no pain
  + Heerfordt syndrome (uveoparotid fever): uveitis, parotitis, cranial nerve
  palsies, subacute meningitis, and systemic sx.
  + posterior uveitis: blurry vision
  + chronic meningitis
  + cardiac: v. tach, heart blocks, CHF, pericarditis, vent. aneurysm
  + bone cysts
  + rarely:  cirrhosis, nasal, laryngeal
  + hypercalcemia and hypercalciuria
 - erythema nodosum (90% of those with sarcoid develop it)
 - skin granulomas (usually in chronic and persistent Stage III)
  + lupus pernio: bluish-purple swelling on nose, cheeks, earlobes, fingers
  and toes, lips, or knees.
  + violaceous, angular, flat plaques with a raised edge
  + psoriasis-like plaques
  + nodules

þ Treatment:
 - prednisone 40-60 mg QD to start
 - 15 mg QOD for maintenance
 - chloroquine for skin lesions

þ Erythema Nodosum association:
 - 90% of those with Erythma Nodosum will have Stage I, and 10% will have
   Stage II;
 - If e. nodosum on presentation, remission likely.

þ Airway Disease:
 - Mostly restrictive, rarely obstructive

þ Lofgren Syndrome
 - Fever, bilateral hilar nodes, arthralgia or arthritis, and erythema nodosum