URIs
                                ====

þ For viral URIs, antihistamines and expectorants do nothing.
  [Hendeles L. Efficacy and safety of antihistamines and expectorants in
  nonprescription cough and cold preparations.  Pharmacotherapy 1993;13(2):154.
  [Naclerio RM. The role of histamine in allergic rhinitis.  J Allergy Clin
  Immunol 1990;86:628-32.]

þ Sympathomimetics vs. BP
 - Sympathomimetics (such as pseudoephedrine) should be avoided in patients
   who may have obstructive uropathy, as they can cause constriction of the
   bladder neck leading to urinary retention.
   Reference:  Tintinalli 3rd ed. p 387

þ Codeine is useless for the cough of a URI.
  [Eccles R. Lack of effect of codeine in the treatment of cough associated
  with acute upper respiratory tract infection.  J Clin Pharm Ther
  1993;17(3):175.]

þ For viral URI, acetaminophen (e.g., Tylenol) or aspirin (but not ibuprofen)
  will:
 - increase nasal stuffiness
 - decrease the subsequent immune response (and presumably resistance to
   re-infection with same virus)
 - probably lengthen the period of viral shedding.
 [Graham NMH, Burrell CJ, Douglas RM, Debelle P, Davies L. Adverse effects of
 aspirin, acetaminophen, and ibuprofen on immune function, viral shedding, and
 clinical status in rhinovirus-infected volunteers. J Infect Dis
 1990;162:1277-82.]