Spider Bites ============ þ Widow Spider Bites - Antivenin (Lyovac) + may be useful up to 30 hours after a bite [Suntorntham S, Roberts JR, Nilsen GJ. Dramatic clinical response to delayed administration of black widow spider antivenin. Ann Emerg Med 1994;24(6):1198-9.] þ Recluse Spider Bites - Not found N. of I-80 in the NW - Pyoderma gangrenosum may be a complication of recluse bites. - Dapsone vs. HBO once you see necrosis - One study shows that most things we think are necrotic spider bites aren't. Study of 600 suspected spider bites. Found 80% caused by other arthropods, and 10% from other disease states. [Russell FE, Gertsch WJ. For those who treat spider or suspected spider bites. Toxicon. 1983;21:337-339.] - Dapsone: + also used for pneumocystis in AIDS , leprosy, and dermatitis herpetiformis + unsafe for use in Porphyria + dapsone may cause methemoglobinemia þ Tegenaria Agrestis (hobo spider, common aggressive house spider) - found mostly in Pacific NW - can have necrosis just like brown recluse bites, but these spider bites can be found further north than brown recluse. - Anecdotal reports (Jim Blackman, M.D., Boise, ID) of success with Dapsone in these bites (one bite got worse after Dapsone stopped then got better when restarted).