Long QT Syndrome
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þ Pathophysiology
 - caused by congential defects (mutations)
 - associated with SIDS
   [Schwartz PJ, Stramba-Badiale M, Segantini A, et al. Prolongation of the QT
   interval and the sudden infant death syndrome [see comments] N Engl J Med
   1998; 338 1709-14]
   Abstract:  <QTa.TXT -infant death>
 - associated with syncope and sudden death; one kind provoked by loud noises,
   another kind provoked by swimming.
   [Moss AJ, Robinson JL, Gessman L, et al. Comparison of clinical and genetic
   variables of cardiac events associated with loud noise versus swimming
   among subjects with the long QT syndrome Am J Cardiol 1999; 84 876-9.]
   Abstract: <QTa.TXT -clinical and genetic>

þ Treatment
 - Beta blockers help but don't prevent death and syncope
   [Moss AJ, Zareba W, Hall WJ, et al. Effectiveness and limitations of
   beta-blocker therapy in congenital long-QT syndrome Circulation 2000; 101
   616-23.]
   Abstract: <QTa.TXT -limitations of beta>