Hyperemesis Gravidarum ====================== þ Role of B6 - Pyridoxine (vitamin B6) may be an etiologic factor for this condition. Therefore, pyridoxine supplementation may be recommended for these patients. Logan and Sayah: "Pregnancy, Hyperemesis gravidarum" in Plantz and Adler's EMedicine, www.emedicine.com/emerg/topic479.htm - Per Dr. Hamm (OB-GYN, Venango Co., PA), the old Bendectine is actually: Unisom (doxylamine succinate 25 mg, an antihistamine) + Vitamin B6 50 mg. Take this at night QHS. þ The Magee formula - B6 (pyridoxine) 50 mg PO BID - Unisom 12.5 mg (1/2 tab) PO BID; not approved for pregnancy but in common use and thought to be OK (2007)