Flexeril in Myofascial Strain study October, 2000 INCLUSION CRITERIA All DEM patients are to be included in the study if they have: - Acute myofascial strains due to minor trauma EXCLUSION CRITERIA Patients will be excluded from the study if they: Have taken any analgesic within 4 hours of arrival to DEM Have known: - Pregnancy - Lactation - Acute Intoxication - Suspected substance abuse - Head injuries - History of hypersensitivity to ibuprofen or cyclobenzaprine Are unable to give informed consent Have potential drug interactions from: - Tricyclic antidepressant medications - CNS depressants - MAO inhibitors Have potential anticholinergic side effects from cyclobenzaprine, patients with known history of: - Urinary retention - Prostatic hypertrophy - Cardiac dysrhythmias - Narrow angle glaucoma Have know history of: - Peptic ulcer disease - Renal insufficiency