Diabetes ======== þ Diabetes Basics þ Unusual causes of hyperglycemia - iron poisoning þ Diabetic Ketoacidosis þ Insulin Types, Onset, Peak and Duration and Insulin Drips þ Urine vs. Serum Ketones - Urine ketones are MORE sensitive than serum; only get them in detectable amounts in the serum once the urinary excretion threshold is exceeded. - Therefore, if urine negative for ketones, no need to check serum. --Jann Johnston, M.D., Endocrinologist, Mercy Hospital of Pittsburgh [Hendey GW, Schwab T, Soliz T. Urine ketone dip test as a screen for ketonemia in DKA and ketosis in the ED. Ann Emerg Med 1997;29(8):735-8.] þ Urine Fructosamine - Fructosamine level is a measure of the integrated glucose values over a few days, similarly to glycated hemoglobin (but fructosamine spans a much shorter period of time, i.e. days instead of weeks). þ ADA diet: - new (1997) guidelines from the ADA emphasizes CONSISTENT CARBOHYDRATE INTAKE at each meal. [American Diabetes Association. Translation of the Diabetes Nutrition Recommendations for Health Care Institutions. Diabetes Care Jan 1997; 20[suppl 1]:537-539.] - The diet is about 1800 kcal (Calories with a big C) - 50% of the Calories are from carbohydrate + 5 CHO exchanges at breakfast + 4 CHO exchanges at lunch + 4 CHO exchanges at dinner + 2 CHO exchanges at bedtime - order as "CONSISTENT CARBOHYDRATE DIET" þ Anti-Diabetic Drugs