Oral Drugs-- Noncompliance ========================== Noncompliance to filling an ED prescription: 22% {Saunders. AJEM 1987; 5:23.} Not related to sex, ability to pay. Short-term oral antibiotic compliance: increasing by only one more time a day to take the pill increases noncompliance by 72%; more complex instructions (with meals, empty stomach, etc.) also decreased compliance. {Sockburn et al. Br Med J 1987; 195:814.}