Clinical Policy for the Management and Risk Stratification of Community-Acquired Pneumonia in Adults in the Emergency Department March 14, 2001 Inclusion criteria This clinical policy is intended for patients 18 years of age or older with clinical and radiologic evidence of pneumonia. Patients arriving at the ED from nursing homes are included. Exclusion criteria Patients excluded from this policy are those who are critically ill or who require respiratory support in the ED. Excluded also are patients with hospital-acquired pneumonia, patients with pneumonia rehospitalized within 30 days of their previous hospitalization, patients who are pregnant, and patients with HIV or who are otherwise immunocompromised. If a patient is younger than 51 years and has no coexisting illnesses or no abnormal physical examination findings, then risk class=I. OTHERWISE, circle the following characteristics and add up the score to determine the risk class. Description of patients in the various risk classes Class I: young (median age, 35 to 37 years); none have pertinent coexisting illnesses or abnormalities. Class II: typically middle-aged (median age, 58 to 59 years); most are assigned to this group by virtue of age alone. Class III: typically older (median age, 72 years), and most had at least one pertinent coexisting illness, one physical examination abnormality, or one laboratory or radiographic abnormality. Classes IV and V: somewhat older (median age, 75 years) and never assigned to the class by virtue of age alone; the majority had abnormalities in 2 (Class IV) or all 3 (Class V) of the pertinent risk factor categories. This classification scheme, which is based on the PSI, potentially has utility to the emergency physician. All Class I patients and many in Classes II and III are likely candidates for outpatient treatment. The remaining Class II and III patients may be candidates for a short hospital stay (< 24 hours). Level A recommendations. Hospitalize patients in PSI Class IV and V. Level B recommendations. Identify low-risk patients eligible for outpatient therapy by using the PSI. BLOOD CULTURES TO DETERMINE CAUSATIVE ORGANISM The utility of blood cultures to determine the etiologic agent in unselected patients with CAP is low, ranging from 6% to 11%, with most isolates being Streptococcus pneumoniae. Furthermore, the presence of a positive blood culture infrequently changes empiric patient management. However, in those patients with severe pneumonia and/or associated risk factors, the incidence of positive blood cultures may approach 30%. Blood cultures may isolate uncommon etiologic organisms (ie, gram-negative organisms or yield agents) demonstrating unusual antibiotic resistance patterns. Precise demonstration of the etiologic agent permits judicious antibiotic use. In the elderly, obtaining blood cultures within 24 hours of admission was associated with reduced 30-day mortality. Blood culture recommendations: Level C recommendations. Obtain blood cultures in all hospitalized patients with CAP. Sputum Gram stain/culture recommendations: Level C recommendations. Consider sputum culture and Gram stain on adequate specimens in high-risk patients who are hospitalized. Empiric therapy of CAP recommendations: Level C recommendations. As one option, consider antibiotic therapy as outlined in the Appendix. Administration of antibiotics for admitted patient recommendations: Level B recommendations. Start antibiotics in all hospitalized patients diagnosed with CAP, and within 8 hours in patients 65 years or older.