Antibiotic Toxicity
                        ===================
þ Quinolones and MG
 - may exacerbate myasthenia gravis weakness (new FDA labeling required 3/11)

þ Quinolone CNS Toxicity
 - Quinolones, and, more rarely, penicillin or cephalosporins, may cause
   coma, confusion, psychosis or seizures
   [Walton G, et al.  Ofloxacin-Induced Seizure Ann Pharamacotherapy 1997;
   31:1475.]
   [Clin Infect Dis 195;21:1504]
   [Reeves R. Ciprofloxacin-Induced Psychosis. Ann Pharmacotherapy 1992:28:931.]
   [Eur J Clin Microbiol 1986;5:226.]
   [Ann Intern Med 1989;110:170.]
   [Rev Infect Dis 1988;10:528.]
   [Jay G. Ciprofloxacin-Induced Delirium. Ann Pharmacotherapy 1997;31:252]
   [J Am Geriatr Soc 1991; 39:909.]
   [Gen Hosp Psychiatry 1995;17:47.]

þ Quinolone Tendinitis
 - all quinolones known for causing tendinitis
 - may occur up to days or weeks after a short course
 - Achilles tendon most common
 - rupture may occur

þ TCN Tetracyclines
 - cause staining of teeth and bones if given in childhood
 - photosensitivity
 - associated with pseudotumor cerebri