Allergy ======= Allergy Classification Anaphylaxis Angioedema Antibiotic Allergy Beestings Contact Dermatitis H2 Blockers for Allergy Urticaria þ Allergy History - if one or more parent has allergy to antibiotics, then 37% of kids will have allergy to an antibiotic by age 16; if neither parent has allergy, less than 2% by age 16 - Sensitivity declines over time "outgrow allergies" + 1 year after allergic reaction, 90% still have IgE + 10 years later, only 10-20% have IgE References: Boxer MB, Greenberger PA, Patterson R: The impact of prednisone in life- threatening idiopathic anaphylaxis: reduction in acute episodes and medical costs. Ann Allergy 1989; 62:201-204 Grant JA, Alam R, Lett-Brown: Histamine-releasing factors and inhibitors: historical perspectives and possible implications in human illness. J Allergy Clin Immunol 1991;88:683-693 Kaliner MA: Nonsedating antihistamines: pharmacology, clinical efficacy and adverse effects. Am Family Physician 1992;45:1337-1342 Mayumi H, Kimura S, Asano M, et al: IV cimetidine as an effective treatment for systemic anaphylaxis and acute allergic skin reactions. Ann Allergy 1987;58:447-450 Moscati RM, Moore GP: Comparison of cimetidine and diphenhydramine in the treatment of acute urticaria. Ann Emerg Med 1990;19:41-44 Yarbrough JA, Moffitt JE, Brown DA: Cimetidine in the treatment of refractory anaphylaxis. Ann Allergy 1989;63:235-238